Hegewald Medizinprodukte
A Reliable And Competent Partner For Single-Use Bioreactors

Managing fluid systems involves overseeing the movement, control and utilization of liquids or gases within various contexts.

For instance, some might need specialized bags or transfer systems tailored to their particular applications. Similarly, there are companies who seek comprehensive solutions for their machinery or operations and require the expertise to integrate it seamlessly into their existing systems or processes.

This significant market demand first soared in the 1990s, leading Jürgen Hegewald and his wife to establish a small company in their garage in Lichtenberg.

Soon after, their son, Robert Hegewald, took over and founded Hegewald Medizinprodukte (HMP) in 1999. The family business produced bags and transfer lines and expanded to create advanced machines like syringe pumps and sensors for contactless measurement of fluid volumes.

Establishing a Solid Professional Foundation

HMP offers high-quality solutions that comply with strict regulations and meet precise material specifications. In 2011, Hegewald launched a distribution company, HEgewald MEdical DIStribution (HEMEDIS), which has since achieved significant success with its total parenteral nutrition (TPN) product line. Currently, the primary focus of HEMEDIS is on the transfer and mixing of fluids from pharmaceutical source containers into bags, syringes, elastomeric pumps, vials and cassettes. The company adheres to stringent standards of accuracy, traceability, cleanliness and documentation throughout these processes.

“Our business success is built on customization, flexibility and quality,” says Robert Hegewald, CEO of Hegewald Medizinprodukte. “We have trademarks like ‘MIB,’ ‘MIBMIX,’ ‘Mixi,’ and ‘Fluicheck,’ promoted by distribution partners across Brazil to Indonesia, establishing the necessary reputation in the market.”

HEMEDIS is a market leader in Germany, offering compounders, disposables and services for individual TPN. Its devices, like the C1 mini compounder, cover various medical segments efficiently, including pain treatment and antibiotic therapy and extend its reach to the oncology segment with a new two-channel device. In 2023, Hemedis introduced a new two-channel MIBMIX targeting oncology, pain treatment, and antibiotics. The response has been overwhelmingly positive. The first production was sold out within a couple of weeks.

Providing a Secure, Efficient and Flexible Fluid Management Solution

Brands such as Hemedis and Mixing Infusion Bag (MIB) collaborated with external experts to develop a new compounder for the mixing of TPN. Obviously, it was named MIBMIX, aligning with the brand of the disposables. The device was a big success. In 2013, it was the first compounder with 12 independent physical channels. Currently, it offers scalability ranging from one to 24 channels.

To improve flexibility, a modular system was patented to address the impracticality of the initial design, which would have been too large. In the advanced German TPN market, pharmacists particularly appreciated the benefits of multi-chamber bags and the reliable automated documentation offered by MIBMIX. This innovative system provides a flexible alternative to the standard compounders of major market players that rely on outdated peristaltic pumps. MIBMIX’s modern approach has given it a significant advantage, leading to its current status as the highest-selling compounder in Germany.

Pharmacists prioritize consistency and maintain rigorous safety standards. Generally, they are averse to change due to the associated risks. However, there inevitably comes a point where change is necessary to meet the needs of patients and the market.

We Have Trademarks Like ‘Mib,’ ‘Mibmix,’ ‘Mixi,’ And ‘Fluicheck,’ Promoted By Distribution Partners Across Brazil To Indonesia, Establishing The Necessary Reputation In The Market

Here, Hemedis provides a secure, efficient and flexible fluid management solution that has demonstrated its efficacy across numerous use cases. It is suitable for small pharmacies as a standalone unit, as well as for large compounding centres producing several hundred bags, where all data is managed using software solutions such as SAP.

In 2015, the groundbreaking Fluicheck^®-Sensor was developed and patented, revolutionizing the process of non-invasive measurement of every single syringe channel. This innovation allows for parallel filling and true mixing with multiple syringe channels, enabling individual monitoring of each substance. The Fluicheck^®-Sensor represents a significant paradigm shift in the industry. Furthermore, the system can be combined with gravimetric measurement, supporting all major laboratory-scale brands and providing a comprehensive solution for precise, efficient fluid handling and measurement.

Focusing on Flexible Containers and Transfer Systems

The company’s user-friendly approach, unlike costly and inflexible robotic solutions, has earned high satisfaction among early adopters. Its devices are recognized for their sustainability, featuring medical-grade stainless steel housings, a modular expendable concept, and the capability to upgrade the system over time, demonstrating HMP’s dedication to environmental responsibility. Additionally, the company’s success is bolstered by its efficient distribution, offering prompt delivery of disposables within 24 hours across Germany. HMP continues to grow, with 60 percent of the business focusing on flexible containers and transfer systems. For pharmaceutical customers with complex cell processing units, it provides around 20 bags along with numerous sensors and transfer lines. While the demand for standard 2D or 3D large bags during the COVID-19 pandemic, mainly used in vaccine production, slowed down, HMP has remained a reliable partner to its customers.

HMP excels at meeting customers’ specific requirements, such as crafting custom-shaped bags for cell preservation that adhere to precise specifications.

For instance, a customer may have a complex cell processing unit with intricate demands, including multiple bags, numerous sensors, and complex transfer lines. HMP is well-equipped to handle both scenarios, offering tailored solutions that match customers’ unique needs. The company’s expertise in providing customized, high-quality products ensures that it can address even the most sophisticated and challenging demands.

Maintaining Top-Grade Quality

HMP’s solutions extend beyond pharmaceuticals to other industries, such as the food sector, which benefits from its products. For instance, the management of enzyme cultures often requires a variety of specialized product solutions. The company’s recently constructed cleanrooms support new projects and initiatives across multiple fields. HMP’s expertise in fluid management systems is widely recognized, making it a reliable choice across industries.

As a skilled partner in designing and manufacturing versatile foil containers, HMP excels in providing customized solutions tailored to the specific needs of products in the medical, paramedical, pharmaceutical, and biotechnological sectors. This versatility underscores HMP’s ability to offer high-quality and innovative solutions for diverse applications.

The company is dedicated to ongoing innovation, continually developing novel product solutions tailored to a diverse array of applications for clients. Its state-of-the-art facilities, multiple clean rooms and diverse manufacturing technologies ensure the high-quality production of its offerings.

The company’s track record is a result of its effective communication between customers and various departments. It has dedicated teams within each segment of its operations, from distribution to fusion and research and development. The distribution team is pivotal in transmitting real-world problems from customers to the research and development department and eventually to production. In the compounding segment, which involves complex machinery, HMP prioritizes stability and software.

Despite their complexity, the compounders are designed to be as simple as an iPhone yet powerful, allowing users to operate them effortlessly. This simplicity is advantageous in less developed markets, where one skilled individual can set up the system for use by a broader audience. Its holistic approach extends to product development, where the integration of hardware, disposable components, and software is essential.

While pursuing theoretical perfection, it emphasizes the practical functionality of the entire system, including validating elements like tubing sets. What enables HMP to be this precise is its understanding of what works at an abstract level and the implementation of those insights at every stage of the process.

To ensure products meet customer requirements and comply with legal standards, HMP is dedicated to consistently excelling in maintaining top-grade quality at every stage of production, with highly qualified employees conducting extensive and continuous tests. It is on the journey of research to develop more advanced solutions and set new market standards.